![]() Bulgular: Geriatrik grupta ÖHS insidansı anlamlı olarak daha yüksekti (%88,5 vs %77,8) (p=0,04). Hastaların demografik özellikleri, komorbiditeleri, laboratuvar sonuçları, hastaneye yatış verileri, yoğun bakım ünitesi (YBÜ) ihtiyacı ve kalış süreleri, tedavi sonuçları ve mortalite oranları kaydedildi ve karşılaştırıldı. Serbest T3 (sT3) ve/veya serbest T4 (sT4)’ü düşük olan hastalar ötiroid hasta sendromu olduğu kabul edildi. Hastalar geriatrik grup (≥65 yaş) ve kontrol grubu (<65 yaş) olarak iki gruba ayrıldı. Gereç ve Yöntem: Sepsis tanısı alan 203 hasta prospektif olarak değerlendirildi. Bu çalışmada, sepsisli yaşlı hastalarda ÖHS prevalansının belirlenmesi ve prognoz ve mortalite üzerindeki olası etkisinin değerlendirilmesi amaçlandı. Anahtar Kelime:Īmaç: Ötiroid hasta sendromu (ÖHS), serum serbest tiroid hormonlarının azalması ve tiroid stimülan hormonun normal veya azalmış sekresyonu ile kendini gösterir. Thus, simply screening of ESS in septic elderly patients will certainly contribute to treatment decisions and early prediction of complicated clinical course and poor prognosis. ![]() Additionally, approximately two-fold higher mortality and ICU stay risk was documented in the ESS (+) group. ![]() Conclusions: The higher prevalence of ESS (88.5%) in elderly patients with sepsis was clearly demonstrated. Additionally, the decreased levels of fT4 in both the entire group and the geriatric group were significantly associated with mortality and ICU stay (p-value: 0.020 and 0.019, respectively). The mean fT3 was significantly decreased in the deceased patients, and ICU patients (p=0.017). ![]() However, 91.3% of deceased patients in the entire group and all deceased patients in the geriatric group were ESS (+) patients. There was no difference between the groups in regard to mortality rate and ICU stay. Results: The incidence of ESS was significantly higher in the geriatric group (88.5% vs. The demographic characteristics, comorbidities, laboratory results, hospitalization data, intensive care unit (ICU) duration, treatment outcomes, and mortality rates of the patients were recorded and compared. Patients with low free T3 (fT3) and/or free T4 (fT4) were considered to have euthyroid-sick syndrome. They were divided into two groups, a geriatric group (≥65 years), and a control group (<65 years). Material and Methods: Two hundred and three patients diagnosed with sepsis were prospectively evaluated. The study aims to identify the prevalence of ESS in elderly patients with sepsis and evaluate its possible effect on prognosis and mortality. The effect of phenobarbital on plasma thyroid hormone concentrations must be investigated in future studies, as it might be less pronounced than expected.Objective: Euthyroid sick syndrome (ESS) manifests by the decreased level of serum free thyroid hormones and with the normal or decreased secretion of thyroid-stimulating hormone. These results suggest that IE can be a reason for euthyroid sick syndrome in dogs. There was no correlation between the degree of alteration of thyroid hormone concentrations and the time span between the most recent seizure event and blood collection, the type of the most recent seizure event, the duration of the complete seizure history, or the predominant seizure type. ![]() 01) between seizure frequency and plasma thyroid hormone concentrations: the longer the interval between 2 seizure events, the higher the serum total thyroxine concentration. There was a significant correlation (r = 0.363, P =. Thyroid concentrations consistent with euthyroid sick syndrome were diagnosed in 38% of dogs with untreated IE without clinical signs of hypothyroidism or concomitant diseases. Control groups consisted of 34 dogs with IE and receiving anticonvulsants and 19 dogs with secondary epilepsy. Blood samples were taken from 60 dogs with IE before initiation of anticonvulsant therapy. One-hundred thirteen dogs with seizure activity were retrospectively evaluated to determine the influence of idiopathic epilepsy (IE) on thyroid hormone concentrations. In dogs with epilepsy, treatment with anticonvulsant drugs can lead to subnormal plasma thyroid hormone concentrations despite normal thyroid function. Euthyroid sick syndrome is a common finding in dogs and is attributable to nonthyroidal illness or treatment with any of a variety of drugs such as phenobarbital. ![]()
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